Modeling Fluid Structure-Interactions for Biomechanical Analysis of the Human Eye

نویسندگان

  • Edward P. Furlani
  • Anthony Nunez
  • Gianmarco Vizzeri
چکیده

A method is presented for studying and quantifying the biomechanical behavior of the human eye under elevated fluid and structural pressure loading. The approach taken involves a coupled synergistic computer modeling and experimental effort in which numerical models are used to predict the biomechanical response of eye under pressure, and physical cadaveric eye models along with appropriate imaging modalities are used to validate the theoretical predictions of tissue deformation within the eye. The numerical models are based on computational fluid dynamic (CFD) analysis combined with a fully-coupled fluid-structure interaction (FSI) capability. Preliminary numerical modeling results of pressure-induced tissue deformation are demonstrated via application to an idealized eye geometry. A discussion is given of challenges and opportunities of using this approach to advance understanding of biomechanical behavior of the human eye.

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تاریخ انتشار 2012